molecular(a) biota Fundamentals Robert J. Robbins Johns Hopkins University rrobbins@gdb.org cross-file: N_drive:\jhu\ classify\1995\mol-bio.ppt © 1994, 1995 Robert Robbins Molecular biological science: 1 Origins of Molecular Biology Phenotype holy genetic science (1900s) Biochemistry (1900s) Genes Proteins ? The phenotype of an organism denotes its external appearance (size, color, intelligence, etc.). innocent genetics showed that genes gibe the transmission of phenotype from nonpareil generation to the next. Biochemistry showed that at bottom adept generation, proteins had a determining effect on phenotype. For galore(postnominal) years, however, the relationship amid genes and proteins was a mystery. Then, it was found that genes contain digitally encoded instructions that speak the synthesis of proteins. The crucial insight of molecular(a) biology is that hereditary culture is passed between generations in a form that is truly, not met aphorically, digital. intellectual how that digital code directs the concept of life is the goal of molecular biology. Phenotype Classical Genetics (1900s) Biochemistry (1900s) Genes Molecular Biology show: N_drive:\jhu\class\1995\mol-bio.ppt © 1994, 1995 Robert Robbins Proteins Molecular Biology: 2 Classical Genetics (1900s) Phenotype Classical Genetics Genes Proteins CC C C P c cc c Cc F1 C c c C c C Cc C c CC Cc F2 Cc cc Regular numeric patterns of inheritance showed that the passage of traits from one generation to the next could be explained with the assumption that hypothetical particles, or genes, were carried in pairs in adults, however transmitted individually to progeny. File: N_drive:\jhu\class\1995\mol-bio.ppt © 1994, 1995 Robert Robbins Molecular Biology: 3 Classical Genetics During the first fractional of this century, immaculate investigation of the gene establishe d that theoretical objects called genes were! the fundamental units of...If you need to get a full essay, order it on our website: OrderEssay.net
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